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KMID : 0390320080180010298
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Chungbuk Medical Journal
2008 Volume.18 No. 1 p.298 ~ p.305
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Clinical course of Cavitary Pulmonary Tuberculosis
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Lee Kee-Man
Choe Kang-Hyeon
Shin Yoon-Mi
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Abstract
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Purpose: In cavitary pulmonary tuberculosis, we evaluated the microbiologic and radiological characteristics which are associated with the residual cavitary lesions and relapse of tuberculosis.
Materials & Method:Thirty-two patients who had been firstly diagnosed with cavitary pulmonary tuberculosis by computed tomograph were classified into two groups according to the chest X-ray findings on 6 month treatment : without residual cavitary lesions(group I) and with residual cavitary lesions(group II). The microbiological results and findings on chest computed tomograph were analyzed retrospectively. Also these characteristics were analyzed between relapsed patients and non-relapsed patients.
Results: After six month antituberculosis treatment, cavitary lesions were closed in eighteen cases(56.3%) and remained in fourteen cases(43.7%) on chest X-ray. Age, cavity size, thickness of cavity wall, involvement of other lobe. Patients with residual cavities had more cavitary lesions on initial chest computed tomography(p=0.036) and more frequent sputum acid fast bacillus smear positivity on two month after treatment(p=0.015). The four patients after completion of treatment were relapsed ( 12.5%) and these four patients who had completed six month treatment regimen had residual cavity after treatment. These relapsed patients also had more cavitary lesions on initial computed tomography(p=0.015).
Conclusions: In cavitary tuberculosis, the patients with residual cavity after six month treatment were more frequently relapsed than those with closed cavity and the presence of residual cavity were associated with initial cavity number and acid fast bacili positivity.
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KEYWORD
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Tuberculosis, Cavitary tuberculosis, Cavity, Relapse
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